IVF Success Rate By Age | What Impacts Your IVF Success?

by Dr. Firuza Parikh

Significant innovations and advances in Assisted Reproductive have been made with the intention of improving success rates which range from 10% to 70% depending on the indications for IVF. Worldwide, more than 9 million babies have been born with the aid of IVF, and other advanced fertility treatments and success rates continue to improve. This blog will delve into the IVF success rates in India and how different factors influence it.

IVF Success Rate By Age: Table of Contents

Tl:DR

IVF success rates in India range from 10% to 70%, depending on various factors such as age and type of infertility.
Age is a major factor, with success rates decreasing significantly after 35 and dropping below 2% after 43.
For women over 40, the chances of IVF success range between 2% and 12%. At age 42, the chances fall to less than 5%. However, preimplantation genetic testing for aneuploidies (PGT-A) can significantly improve success rates.
Factors influencing IVF success include age, fertility issues (endometriosis, PCOS, Premature Ovarian Insufficiency), embryo quality, and sperm quality.
Strategies to improve IVF success include pre-IVF evaluation and preparation, advanced embryo selection techniques like preimplantation genetic testing (PGT), personalized treatment plans, lifestyle changes (exercise, healthy eating, sleep), and a collaborative approach between patients and the fertility clinician.
The success rates for IVF treatments in India have been improving, but it is important to consider all factors and consult with experienced fertility specialists for the best chances of success.

Success rates are dependent on multiple factors.

The couple’s age and the type of Infertility are some of the important factors impacting success rates. The advancing age of a woman has an impact on the amount and quality of the oocytes that are available.

IVF success dramatically drops when the woman is older than 35 years old and approaches less than 2 percent after the age of 43.

The ageing of the male partner has an impact on fertility through its effect on the quality of the sperm. Sperm DNA fragmentation increases with advancing age and in the presence of diabetes, smoking and diseases like hypertension. These damage the sperm DNA, thereby reducing the capacity to fertilize as well as the quality of embryos and can cause miscarriages. Damage to the Sperm DNA is higher in men after the age of 45.

“The success rates of ART vary depending on patient and treatment factors, including age, infertility diagnosis, number of transferred embryos, procedure type, use of procedures like ICSI, and history of prior pregnancies, miscarriages, and ART cycles” (CDC Report 2009)

IVF Success Rates by Age

Successful IVF outcomes are generally higher in younger women, averaging around 40% globally. This likelihood of success increases even more for those under 35 years old. The success of ART is measured by Live Birth Rates, which is the number of live births per embryo transfer.

IVF success rates in India are similar to global rates. Some clinics like ours at Fertiltree are one of the best in India.

Here’s a breakdown of IVF success rate by age in India:

IVF Success Rates under 35

Women in their 20’s to early 30’s are most fertile.

If a woman has conceived before, her chances of conceiving are much better. If a woman have had a child before then her chances of success are greater.

Todd N 2021, revealed, “a woman’s age is a major factor in the success of IVF for any couple and for instance, in 2018, the likelihood of conceiving one child with IVF was 37.6% for a woman under the age of 35 using her own eggs, compared to 11% for a woman between the ages of 41 and 42.

IVF success rates in India are similar to global rates. Some clinics like ours at Fertiltree are one of the best in India. Lower the age, the better are the chances of success.

IVF Success rates over 40

For women at 40 years, the chances are between 2 to 12%.
At 42, the chances fall to less than 5%. However if PGT-A ie Preimplantation Genetic testing for aneuploidies is carried out prior to embryo transfer the chances improve significantly.
For women above 43 years of age, donor eggs may be a better option.

Factors Impacting IVF Success Rates

IVF Success rates are dependent on multiple factors:

Age

As a woman ages, her fertility decreases significantly, leading to a decline in IVF success rates due to the fact that quantity and quality of eggs diminish with age, making it harder to achieve successful fertilization and implantation.

The success rate of IVF treatments tends to dramatically decrease with age, especially when the woman is over the age of 35.

Fertility Issues

Unfortunately, various medical conditions like endometriosis, PCOS and diminished ovarian reserve may impact the outcomes of IVF treatment. These conditions can reduce the number of eggs retrieved, disrupt embryo growth and even prevent implantation.

Embryo Quality

IVF success depends on embryo quality. Morphological and genetic health are two essential components of embryo quality. Embryos with good parameters are more likely to implant successfully in the uterus and produce successful pregnancies. Achieving positive IVF outcomes depends on choosing healthy embryos with normal chromosomal companent and ideal morphology. For this reason, embryo selection is of great importance.

Male Age And Sperm Quality

The ageing of the male partner has an impact on fertility through its effect on the quality of the sperm. Sperm DNA fragmentation increases with advancing age and in the presence of diabetes, hypertension, smoking, infection and varicolce. These damage the sperm DNA, thereby reducing the capacity to fertilize and produce poor quality embryos resulting in miscarriages. Damage to the Sperm DNA increases after the age of 45 years.

What is the best way to improve IVF rate of success?

Despite the advances in medical technologies, IVF success rates vary depending on each individual’s infertility factor. Fortunately, there are strategies and treatments available that can help improve the chances of a successful IVF cycle. From lifestyle changes to innovative techniques such as preimplantation genetic testing and embryo selection, here are some strategies to improve the success rate of IVF.

Pre-IVF Evaluation and Preparation

Before undergoing IVF, it is important to ensure that a thorough evaluation has been done to check ovarian reserve, uterine health, and other potential health issues. Proper evaluation and preparation goes a long way in maximizing the chances of success. Making changes to one’s lifestyle, like maintaining a healthy weight, stopping smoking, and finding ways to reduce stress, can show positive results.

Advanced Embryo Selection Techniques

Preimplantation genetic testing (PGT) is a revolutionary breakthrough, helping us to select the chromosomally normal embryos with greater accuracy.

Utilizing PGT can help to boost successful implantation and reduce the chance of miscarriages. It is an effective way to enhance you chances to build your family.

Treatment Plan

In order to maximise results, couples need tailored treatment plans- customizing medication protocols, altering stimulation methods and using advanced strategies like assisted hatching or blastocyst culture can improve success. Personalization of treatment is the key to a successful outcome.

Lifestyle Changes

For the best results during an IVF procedure, it is essential to find an exercise regimen that works for you and doesn’t over exhaust your body. Proper balance between exercise and rest can significantly improve your chances of success.

Staying active can help reduce stress levels. It is necessary to have a BMI within the healthy range in order to keep up with physical activity. It may be recommended to opt for lighter activities such as walking, jogging or cycling instead of intense exercises such as running. Performing yoga is also a great way to relax and stay active.

For the most effective sperm collection, an abstinence period of 2 days is adequate unlike earlier suggestions for a longer abstinence period.

It is essential to talk with your fertility team or doctor regarding start taking supplements during your pregnancy. Taking prenatal vitamins and vitamin D can help with a healthy pregnancy, but it is best to get medical advice beforehand.

To improve the chances of a successful IVF treatment, adequate sleep is essential. It is recommended to clock an average of 7-8 hours per night. If you are having trouble getting quality sleep, talk to your doctor or fertility expert about the possibility of taking melatonin supplements for better uninterrupted sleep.

Healthy Eating

According to studies, following the Mediterranean Diet for a period of six months prior to IVF could potentially have beneficial effects on IVF outcomes. This type of diet has a variety of fresh vegetables, fruits, whole grains, legumes and fish with moderate consumption of red meat. Researchers say that individuals who followed this specific diet for at least 6 months prior to receiving IVF had an upsurge of success to 65-68% for successful pregnancy.

Couples who plan to go through IVF should lower their alcohol, tobacco and caffeine intake.

Collaborative Approach

Establishing a strong relationship between IVF centres and their patients is key to ensuring successful treatment. Success relies heavily on regular conversations so expectations can be assessed and joint decisions can be made. Keeping communication open is essential in promoting successful IVF treatments.

IVF Success Rate in India: Final Thoughts

The success rates for IVF treatments in India have improved over the past few years. However numerous variables can affect the success of In-Vitro Fertilization procedures in India. You must take into consideration all possible elements before making any decisions. Understanding these factors and implementing strategies to optimize success, such as comprehensive evaluations, advanced embryo selection techniques, individualized treatment plans, and a collaborative approach, can increase the chances of a successful IVF outcome. Consulting with experienced fertility specialists and seeking support from reputable fertility clinics are essential steps towards achieving the dream of parenthood.