Cumulus Aided Transfer

CAT Enhances IVF Success at Jaslok Hospital and Research Centre

An innovation developed for the first time in the world has dramatically increased the success of IVF. The technique known as CAT (Cumulus-Aided Embryo Transfer), was developed by Dr. Firuza Parikh and her team at Jaslok Hospital and Research Centre in Mumbai.

Dr. Firuza Parikh describes the technique as follows, “We have harnessed nature to improve pregnancy rates. The embryos are transferred into the uterus along with cumulus cells. These cells surround the oocyte at the time of ovulation. After oocyte retrieval, the cumulus cells are usually discarded. Instead, we allow them to grow in the laboratory as the cells are rich in factors, which facilitate the growth of embryos. At the time of embryo transfer, droplets of cumulus cells are added to the embryos.”

In an earlier study, CAT was carried out in 507 women, more than half of whom had failed IVF attempts in the past. In this group of women, pregnancy rates increased to 46%. This data was published in the scientific journal Fertility and Sterility, October 2006.

Cumulus Aided Transfer (CAT) is especially useful in cases with previous unsuccessful IVF attempts, in older women and in cases where fewer oocytes are obtained.

Dr. Parikh adds that “IVF is not merely a science, it is also a meticulous art. You look into the little details, work with nature instead of trying to outsmart it and always strive towards improving pregnancy rates – CAT is a movement in that direction.”

CAT is useful for women with previous unsuccessful IVF attempts, in older women and when less number of oocytes are obtained. Scientific data on this procedure was published in the prestigious and leading international  Scientific Journal, Fertility & Sterility (Reference “Cumulus coculture and cumulus-aided embryo transfer increases pregnancy rates in patients undergoing in vitro fertilization

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